Medical professionals performing surgery on a patient, using surgical tools and wearing scrubs, gloves, and masks.

Clinical Evidence

Published studies relevant to our dental portfolio

We believe clinicians should have easy access to evidence. Below are selected peer-reviewed publications where CenoBone®, CenoMembrane® and CenoDerm® are described in dental/periodontal applications.

*Note: Individual outcomes vary. These summaries do not replace IFUs, training, or clinician judgement.

X-ray image of a human skull showing teeth and nasal cavity.

1) Lateral ridge augmentation: CenoBone®/CenoMembrane® vs Bio-Oss®/Bio-Gide®

Study type: Randomised controlled clinical trial (preliminary)

Summary: Compared two graft + membrane complexes for lateral ridge augmentation. Reported comparable radiographic, histologic, and histomorphometric outcomes at 6 months, with some differences in specific parameters.

PubMed: https://pubmed.ncbi.nlm.nih.gov/27857771/

Full text (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC5091004/

2) Ridge preservation (extraction sockets): CenoBone® with and without PRGF

Study type: Clinical trial

Summary: Evaluated clinical, histologic, and histomorphometric outcomes when CenoBone® was used alone versus combined with PRGF in extraction socket ridge preservation.

PubMed: https://pubmed.ncbi.nlm.nih.gov/36960023/

Full text (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC10028575/

3) Soft tissue (ADM) case report: CenoDerm® for multiple gingival recessions

Study type: Case report with one-year follow-up

Summary: Described use of CenoDerm® with a coronally positioned flap for multiple gingival recession defects, reporting outcomes at one year.

PubMed: https://pubmed.ncbi.nlm.nih.gov/25346839/

Full text (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC4206762/

Wider context: ADM in periodontal and implant plastic surgery (category-level)

Systematic reviews and clinical trials discuss ADM approaches (as a category) across periodontal and implant plastic surgery.

Systematic review (ADM category): https://doi.org/10.1016/j.ijom.2019.12.005